Coming from macromolecular and surface chemistry background, Shlomo Yitzchaik developed novel routes to assemble molecules on surfaces including the topotactic self-assembly (TSA) and the molecular layer epitaxy (MLE) methodologies that are applicable to solid-state 2D-surfaces. He pioneered the studies for molecular tuning of the electronic properties of silicon. In addition, he has developed a modular method to link molecular transducers to various sensor-devices surfaces that interfaces living cells with electronic devices. Prof. Yitzchaik also explored new photoactive conducting nanowires and gels. From 1995-present he has an academic appointment in the institute of Chemistry, Hebrew University of Jerusalem. He received his PhD in 1992 from the Weitzman Institute of Science in Israel and spend 3 years as a post doctoral fellow at Northwestern University. He has authored over 100 papers and holds 17 patents in the fields of material science, solid-state organic chemistry and thin-film technologies. Some of the awards he has received include the Israeli Chemical Society, the prestigious Kaye Award from the Hebrew University as well as the Israel Vacuum Society’s award for his development and contribution in the field of molecular layers.